These ‘Exploding’ Capsules Could Deliver Insulin Without a Needle

admin — Tue, 08 Jul 2025 13:22:30 +0000

These ‘Exploding’ Capsules Could Deliver Insulin Without a Needle admin Tue, 07/08/2025 - 09:22

Georgia Tech engineers have created a pill that could effectively deliver insulin and other injectable drugs, making medicines for chronic illnesses easier for patients to take, less invasive, and potentially less expensive.

Along with insulin, it also could be used for semaglutide — the popular GLP-1 medication sold as Ozempic and Wegovy — and a host of other top-selling protein-based medications like antibodies and growth hormone that are part of a $400 billion market.

These drugs usually have to be injected because they can’t overcome the protective barriers of the gastrointestinal tract. Georgia Tech’s new capsule uses a small pressurized “explosion” to shoot medicine past those barriers in the small intestine and into the bloodstream. Unlike other designs, it has no complicated moving parts and requires no battery or stored energy.

“This study introduces a new way of drug delivery that is as easy as swallowing a pill and replaces the need for painful injections,” said Mark Prausnitz, who created the pill in his lab with former Ph.D. student Joshua Palacios and other student researchers.

In animal lab tests, they showed their capsule lowered blood sugar levels just like traditional insulin injections. The researchers reported their pill design and study results DATE in the Journal of Controlled Release.

Read about the technology on the College of Engineering website.

Summary sentence

Engineers use sodium bicarb to “self-pressurize” a pill able to deliver drugs that usually require injection directly to the small intestine.

Summary

Engineers use sodium bicarb to “self-pressurize” a pill able to deliver drugs that usually require injection directly to the small intestine.

Dateline

Tue, 07/08/2025 - 12:00

jstewart@gatech.edu

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Joshua Stewart
College of Engineering

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Mark Prausnitz Elected to National Academy of Engineering

admin — Thu, 09 Feb 2023 19:52:53 +0000

Mark Prausnitz Elected to National Academy of Engineering admin Thu, 02/09/2023 - 14:52

Professor and entrepreneur Mark Prausnitz has been elected to the National Academy of Engineering (NAE), joining a membership that includes the nation’s most distinguished engineers. He is Georgia Tech’s 46th NAE member.

Prausnitz is the J. Erskine Love Jr. Chair of the School of Chemical and Biomolecular Engineering (ChBE) and director of Georgia Tech’s Center for Drug Design, Development and Delivery. He’s also the only Georgia Tech faculty member recognized as both a Regents’ Professor and Regents’ Entrepreneur, the highest academic titles awarded by the University System of Georgia Board of Regents. He joins 105 new NAE members in the 2023 class along with 18 new international members.

Read the full story on the College of Engineering website.

Summary sentence

The honor is one of the highest professional distinctions for engineers

Summary

The honor is one of the highest professional distinctions for engineers

Dateline

Tue, 02/07/2023 - 12:00

maderer@gatech.edu

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Jason Maderer
College of Engineering

Location

Atlanta, GA

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Mark Prausnitz

School of Chemical and Biomolecular Engineering

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665671

Source updated

Thu, 02/09/2023 - 14:18

Mark Prausnitz

These ‘Exploding’ Capsules Could Deliver Insulin Without a Needle

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Mark Prausnitz Elected to National Academy of Engineering

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